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Maria Serena Fabbrini Selected Research

Saporins

1/2021Aptamer-Driven Toxin Gene Delivery in U87 Model Glioblastoma Cells.
1/2018Strategies to Improve the Clinical Utility of Saporin-Based Targeted Toxins.
10/2017Plant Ribosome-Inactivating Proteins: Progesses, Challenges and Biotechnological Applications (and a Few Digressions).
11/2016Optimization of construct design and fermentation strategy for the production of bioactive ATF-SAP, a saporin based anti-tumoral uPAR-targeted chimera.
1/2009Saporin suicide gene therapy.

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Maria Serena Fabbrini Research Topics

Disease

6Neoplasms (Cancer)
01/2018 - 01/2009
1Glioma (Gliomas)
01/2021
1Virus Diseases (Viral Diseases)
10/2017
1Lymphoma (Lymphomas)
02/2015
1Melanoma (Melanoma, Malignant)
01/2009
1Experimental Melanoma
01/2009

Drug/Important Bio-Agent (IBA)

5SaporinsIBA
01/2021 - 01/2009
2Immunotoxins (Immunotoxin)IBA
01/2018 - 02/2015
2Ribosome Inactivating ProteinsIBA
01/2018 - 11/2010
2AntibodiesIBA
01/2018 - 02/2015
2Immunoglobulin FragmentsIBA
01/2018 - 02/2015
2Proteins (Proteins, Gene)FDA Link
11/2016 - 02/2015
1PolyethyleneimineIBA
01/2021
1NucleolinIBA
01/2021
1Glycoside Hydrolases (Endoglycosidases)IBA
10/2017
1RicinIBA
10/2017
1Urokinase-Type Plasminogen Activator (Urokinase)FDA Link
11/2016
1Urokinase Plasminogen Activator ReceptorsIBA
11/2016
1AntigensIBA
02/2015
1Differentiation AntigensIBA
02/2015
1Single-Chain AntibodiesIBA
02/2015
1LuciferasesIBA
01/2009
11,2- dioleoyloxy- 3- (trimethylammonium)propaneIBA
01/2009
1LipofectamineIBA
01/2009
1DNA (Deoxyribonucleic Acid)IBA
01/2009
1methyl sulfateIBA
01/2009

Therapy/Procedure

2Therapeutics
01/2018 - 11/2010
1Injections
01/2009